7-keto
7-keto is a ingredient found in several different over the counter diet pill products. The reason for this is because of clinical trial studies that have shown a significant increase in weight loss in humans supplemented witht this ingredient. Don’t get too excited about the word significant change stated in the study, in scientific terms it just means a notable difference. That doesn’t mean that 7-keto won’t make a significant difference for your weight loss though. There are several different ways that this compound works at increasing thermogenesis to help you burn more calories during the day without having to any extra work. One thing to note about 7-keto is that when you do work out while using this supplement it increases fat loss even faster. Lets take a look at some of the ways 7-keto works toward decreasing body fat and increasing calorie consumption in the body.
7-keto & Weight Loss
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7-keto DHEA is said to be clinically proven to increase metabolism and contribute to an increase in weight loss. The 7-keto contributes to weight loss is by increasing the activity of thermogenic enzymes responsible for fatty acid oxidation. Studies show that 7-keto supplementation increases acyl CoA-oxidase by 128 percent, malic enzyme by 860 percent, and glycerol-3-phosphate dehydrogenase by 138 percent. A double-blind, placebo-controlled study on 30 overweight adults showed a 6.3-lb. decrease in body fat, compared to 2.1 pounds placebo. More of the weight lost was said to be body fat in the 7-keto group. Thryroid hormone was slightly elevated in people using 7-keto, but no other side effects were reported. Combined with diet and exercise, 7-keto has been shown to accelerate fat loss.
Immune Health
7-keto DHEA has also been linked to improving immune function. Monkeys infected with simian HIV experienced a five-fold increase in T cells, with 7-keto DHEA supplementation. The Minnesota Applied Research Center performed a four-week human clinical trial to determine the effects of 7-keto on elderly men and women. Using 100mg two times a day, the subjects experienced improved immune function, as well as an increase in immune helper cells, increased white blood cells and decreased blood pressure.
Effects on Aging
7-keto naturally declines with age. The levels of 7-keto rise until age 20. By 30, blood concentrations begin to decline, reducing by up to 50 percent at age 50. Decreases in DHEA and 7-keto can lead to dominance of the stress hormone cortisol, which can contribute to aging and disease. A Czech study evaluated the effect of 7-keto on markers for heart disease. Only 25mg per day for five days significantly raised HDL or good cholesterol. The total cholesterol reduction was low, but the atherogenic index–a measure for risk of cardiovascular disease–showed marked improvement. 7-keto may also help to improve brain function by helping neurons establish contact with others, increasing efficiency in the aging brain. A leading researcher of 7-keto, Dr. Henry Lardy, states that 7-keto provides many of the benefits of DHEA supplements with none of the side effects. A 28-day human safety trial on 7-keto showed no conversion to male or female sex hormones and no effect on blood and urine chemistry. At 200mg per day of 7-keto, no side effects were reported.
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